BDBM50164225 CHEMBL365470::N-[6-(Imidazo[1,2-d][1,2,4]thiadiazol-3-ylamino)-hexyl]-2-methyl-benzenesulfonamide

SMILES: Cc1ccccc1S(=O)(=O)NCCCCCCNc1nsc2nccn12

InChI Key: InChIKey=SHCHYVBWWCFVCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XIII (Homo sapiens (Human))	BDBM50164225 (CHEMBL365470 | N-[6-(Imidazo[1,2-d][1,2,4]thiadiaz...) Show SMILES Cc1ccccc1S(=O)(=O)NCCCCCCNc1nsc2nccn12 Show InChI InChI=1S/C17H23N5O2S2/c1-14-8-4-5-9-15(14)26(23,24)20-11-7-3-2-6-10-18-16-21-25-17-19-12-13-22(16)17/h4-5,8-9,12-13,20H,2-3,6-7,10-11H2,1H3,(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Apotex Research Inc. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of compound against factor XIIIa				J Med Chem 48: 2266-9 (2005) Article DOI: 10.1021/jm049221w BindingDB Entry DOI: 10.7270/Q2R210XM
					More data for this Ligand-Target Pair