new BindingDB logo
myBDB logout

BDBM50164225 CHEMBL365470::N-[6-(Imidazo[1,2-d][1,2,4]thiadiazol-3-ylamino)-hexyl]-2-methyl-benzenesulfonamide

SMILES: Cc1ccccc1S(=O)(=O)NCCCCCCNc1nsc2nccn12

InChI Key: InChIKey=SHCHYVBWWCFVCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164225   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor XIII


(Homo sapiens (Human))
BDBM50164225
PNG
(CHEMBL365470 | N-[6-(Imidazo[1,2-d][1,2,4]thiadiaz...)
Show SMILES Cc1ccccc1S(=O)(=O)NCCCCCCNc1nsc2nccn12
Show InChI InChI=1S/C17H23N5O2S2/c1-14-8-4-5-9-15(14)26(23,24)20-11-7-3-2-6-10-18-16-21-25-17-19-12-13-22(16)17/h4-5,8-9,12-13,20H,2-3,6-7,10-11H2,1H3,(H,18,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Apotex Research Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of compound against factor XIIIa


J Med Chem 48: 2266-9 (2005)


Article DOI: 10.1021/jm049221w
BindingDB Entry DOI: 10.7270/Q2R210XM
More data for this
Ligand-Target Pair