BDBM50164292 CHEMBL3798888

SMILES: CCN1c2cc(ccc2C(=O)NC1(C)C)-c1cn[nH]c1

InChI Key: InChIKey=ASEAOWRSJOFNLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50164292 (CHEMBL3798888) Show SMILES CCN1c2cc(ccc2C(=O)NC1(C)C)-c1cn[nH]c1 Show InChI InChI=1S/C15H18N4O/c1-4-19-13-7-10(11-8-16-17-9-11)5-6-12(13)14(20)18-15(19,2)3/h5-9H,4H2,1-3H3,(H,16,17)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...				Bioorg Med Chem 24: 2466-75 (2016) Article DOI: 10.1016/j.bmc.2016.04.008 BindingDB Entry DOI: 10.7270/Q27W6F29
					More data for this Ligand-Target Pair