BDBM50164554 (2R,3S)-1-[(E)-(3-Phenyl-acryloyl)]-piperazine-2,3-dicarboxylic acid::CHEMBL363649

SMILES: OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)\C=C\c1ccccc1

InChI Key: InChIKey=KUBGBPOSXKHQAN-VFZNBBLXSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50164554 ((2R,3S)-1-[(E)-(3-Phenyl-acryloyl)]-piperazine-2,3...) Show SMILES OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H16N2O5/c18-11(7-6-10-4-2-1-3-5-10)17-9-8-16-12(14(19)20)13(17)15(21)22/h1-7,12-13,16H,8-9H2,(H,19,20)(H,21,22)/b7-6+/t12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50164554 ((2R,3S)-1-[(E)-(3-Phenyl-acryloyl)]-piperazine-2,3...) Show SMILES OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H16N2O5/c18-11(7-6-10-4-2-1-3-5-10)17-9-8-16-12(14(19)20)13(17)15(21)22/h1-7,12-13,16H,8-9H2,(H,19,20)(H,21,22)/b7-6+/t12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50164554 ((2R,3S)-1-[(E)-(3-Phenyl-acryloyl)]-piperazine-2,3...) Show SMILES OC(=O)[C@H]1NCCN([C@H]1C(O)=O)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H16N2O5/c18-11(7-6-10-4-2-1-3-5-10)17-9-8-16-12(14(19)20)13(17)15(21)22/h1-7,12-13,16H,8-9H2,(H,19,20)(H,21,22)/b7-6+/t12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair