BDBM50164615 (2R)-3'-(1,3-benzothiazol-2-yl)-2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazolidin]-2'-one::CHEMBL189150

SMILES: O=C1O[C@@]2(CN1c1nc3ccccc3s1)CN1CCC2CC1

InChI Key: InChIKey=JILKSNXBFUMLAW-MRXNPFEDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50164615 ((2R)-3'-(1,3-benzothiazol-2-yl)-2'H-spiro[4-azabic...) Show SMILES O=C1O[C@@]2(CN1c1nc3ccccc3s1)CN1CCC2CC1 |wU:3.2,(3.13,3.83,;2.18,2.61,;.64,2.65,;.12,1.21,;1.34,.27,;2.61,1.14,;4.14,1.16,;5.05,-.08,;6.51,.41,;7.85,-.35,;9.18,.44,;9.16,1.98,;7.83,2.72,;6.5,1.94,;5.05,2.4,;.12,-.33,;-1.21,-1.1,;-.74,.16,;-1.84,.79,;-1.21,1.98,;-2.54,1.21,;-2.54,-.33,)| Show InChI InChI=1S/C16H17N3O2S/c20-15-19(14-17-12-3-1-2-4-13(12)22-14)10-16(21-15)9-18-7-5-11(16)6-8-18/h1-4,11H,5-10H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7				J Med Chem 48: 2678-86 (2005) Article DOI: 10.1021/jm049188d BindingDB Entry DOI: 10.7270/Q2M0466W
					More data for this Ligand-Target Pair