BDBM50164679 CHEMBL3798527

SMILES: NC(=O)c1ccc(Cn2cc(Cl)cc(C(N)=O)c2=N)cc1Cl

InChI Key: InChIKey=GEAAIQLKZQDRFZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50164679 (CHEMBL3798527) Show SMILES NC(=O)c1ccc(Cn2cc(Cl)cc(C(N)=O)c2=N)cc1Cl Show InChI InChI=1S/C14H12Cl2N4O2/c15-8-4-10(14(19)22)12(17)20(6-8)5-7-1-2-9(13(18)21)11(16)3-7/h1-4,6,17H,5H2,(H2,18,21)(H2,19,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...				J Med Chem 59: 2989-3002 (2016) BindingDB Entry DOI: 10.7270/Q20G3N2B
					More data for this Ligand-Target Pair