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BDBM50164679 CHEMBL3798527

SMILES: NC(=O)c1ccc(Cn2cc(Cl)cc(C(N)=O)c2=N)cc1Cl

InChI Key: InChIKey=GEAAIQLKZQDRFZ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164679   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50164679
PNG
(CHEMBL3798527)
Show SMILES NC(=O)c1ccc(Cn2cc(Cl)cc(C(N)=O)c2=N)cc1Cl
Show InChI InChI=1S/C14H12Cl2N4O2/c15-8-4-10(14(19)22)12(17)20(6-8)5-7-1-2-9(13(18)21)11(16)3-7/h1-4,6,17H,5H2,(H2,18,21)(H2,19,22)
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CHEMBL
PC cid
PC sid
UniChem
PubMed
65n/an/an/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

Curated by ChEMBL


Assay Description
Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...


J Med Chem 59: 2989-3002 (2016)


BindingDB Entry DOI: 10.7270/Q20G3N2B
More data for this
Ligand-Target Pair