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SMILES: CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(C)cc(C)c1)[N+]([O-])=O

InChI Key: InChIKey=GJFKROIMAOLXMH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164788
PNG
(CHEMBL3800271)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(C)cc(C)c1)[N+]([O-])=O
Show InChI InChI=1S/C20H24N4O3/c1-14-10-15(2)12-16(11-14)20(25)21-18-13-17(24(26)27)4-5-19(18)23-8-6-22(3)7-9-23/h4-5,10-13H,6-9H2,1-3H3,(H,21,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/a 390n/an/an/an/an/a



Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair