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BDBM50164845 CHEMBL3799081

SMILES: Br.C(Oc1cccc2ccn(CC3=NCCN3)c12)c1ccccc1

InChI Key: InChIKey=APBHKFKPXAJWCP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164845   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Imidazoline I1


(RAT)		BDBM50164845
PNG
(CHEMBL3799081)
Show SMILES Br.C(Oc1cccc2ccn(CC3=NCCN3)c12)c1ccccc1 |t:11|
Show InChI InChI=1S/C19H19N3O.BrH/c1-2-5-15(6-3-1)14-23-17-8-4-7-16-9-12-22(19(16)17)13-18-20-10-11-21-18;/h1-9,12H,10-11,13-14H2,(H,20,21);1H
UniProtKB/SwissProt

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PC sid
UniChem

Patents
PubMed
 3.63E+4n/an/an/an/an/an/an/an/a



Medical University of Gdansk

Curated by ChEMBL


Assay Description
Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting

Eur J Med Chem 115: 406-15 (2016)


BindingDB Entry DOI: 10.7270/Q2GH9KVS
More data for this
Ligand-Target Pair