BDBM50164971 (R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-butoxy-phenyl)-amide::CHEMBL370964
SMILES: CCCCOc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1
InChI Key: InChIKey=WNKQCWMJGIIGIP-WJOKGBTCSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50164971 ((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 145 | n/a | n/a | n/a | n/a |
Genzyme Corp. Curated by ChEMBL | Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR | Bioorg Med Chem Lett 15: 2087-91 (2005) Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP | |||||||||||
More data for this Ligand-Target Pair |