BDBM50165065 9-(2,6-Dichloro-benzyl)-6-furan-2-yl-9H-purin-2-ylamine::CHEMBL193414

SMILES: Nc1nc(-c2ccco2)c2ncn(Cc3c(Cl)cccc3Cl)c2n1

InChI Key: InChIKey=JTYVCSYDVGSSFY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50165065 (9-(2,6-Dichloro-benzyl)-6-furan-2-yl-9H-purin-2-yl...) Show SMILES Nc1nc(-c2ccco2)c2ncn(Cc3c(Cl)cccc3Cl)c2n1 Show InChI InChI=1S/C16H11Cl2N5O/c17-10-3-1-4-11(18)9(10)7-23-8-20-14-13(12-5-2-6-24-12)21-16(19)22-15(14)23/h1-6,8H,7H2,(H2,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranes				Bioorg Med Chem Lett 15: 2119-22 (2005) Article DOI: 10.1016/j.bmcl.2005.02.031 BindingDB Entry DOI: 10.7270/Q2542N3H
					More data for this Ligand-Target Pair