BDBM50165122 CHEMBL195283::disodium 2-amino-9-[(2R,4S,5R)-5-[({[(2-carboxylatoethyl)amino]phosphinato}oxy)methyl]-3,4-bis(propan-2-yloxy)oxolan-2-yl]-6-hydroxy-9H-purin-7-ium

SMILES: CC(C)O[C@H]1[C@@H](COP([O-])(=O)NCCC([O-])=O)O[C@H](C1OC(C)C)n1c[nH+]c2c1nc(N)[nH]c2=O

InChI Key: InChIKey=BOGSMJGITWKGPP-NWYBNOCISA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50165122 (CHEMBL195283 | disodium 2-amino-9-[(2R,4S,5R)-5-[(...) Show SMILES CC(C)O[C@H]1[C@@H](COP([O-])(=O)NCCC([O-])=O)O[C@H](C1OC(C)C)n1c[nH+]c2c1nc(N)[nH]c2=O Show InChI InChI=1S/C19H31N6O9P/c1-9(2)32-14-11(7-31-35(29,30)22-6-5-12(26)27)34-18(15(14)33-10(3)4)25-8-21-13-16(25)23-19(20)24-17(13)28/h8-11,14-15,18H,5-7H2,1-4H3,(H,26,27)(H2,22,29,30)(H3,20,23,24,28)/p-1/t11-,14+,15?,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair