BDBM50165127 2-Amino-9-((2R,4S,5R)-5-hydroxymethyl-3,4-diisopropoxy-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one::CHEMBL372079

SMILES: CC(C)O[C@H]1[C@@H](CO)O[C@H](C1OC(C)C)n1cnc2c1nc(N)[nH]c2=O

InChI Key: InChIKey=ZILVDJSDJUEGCF-WABSSEDKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50165127 (2-Amino-9-((2R,4S,5R)-5-hydroxymethyl-3,4-diisopro...) Show SMILES CC(C)O[C@H]1[C@@H](CO)O[C@H](C1OC(C)C)n1cnc2c1nc(N)[nH]c2=O Show InChI InChI=1S/C16H25N5O5/c1-7(2)24-11-9(5-22)26-15(12(11)25-8(3)4)21-6-18-10-13(21)19-16(17)20-14(10)23/h6-9,11-12,15,22H,5H2,1-4H3,(H3,17,19,20,23)/t9-,11+,12?,15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
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