BDBM50165134 2-Amino-7-ethyl-9-((2R,4S,5R)-5-hydroxymethyl-3,4-diisopropoxy-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-7-ium::CHEMBL193326

SMILES: CC[n+]1cn([C@@H]2O[C@H](CO)[C@H](OC(C)C)C2OC(C)C)c2nc(N)[nH]c(=O)c12

InChI Key: InChIKey=FKECPCDTFCIGMF-NUKIEUHSSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50165134 (2-Amino-7-ethyl-9-((2R,4S,5R)-5-hydroxymethyl-3,4-...) Show SMILES CC[n+]1cn([C@@H]2O[C@H](CO)[C@H](OC(C)C)C2OC(C)C)c2nc(N)[nH]c(=O)c12 Show InChI InChI=1S/C18H29N5O5/c1-6-22-8-23(15-12(22)16(25)21-18(19)20-15)17-14(27-10(4)5)13(26-9(2)3)11(7-24)28-17/h8-11,13-14,17,24H,6-7H2,1-5H3,(H2-,19,20,21,25)/p+1/t11-,13+,14?,17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair