BDBM50165135 CHEMBL193790::disodium 2-amino-9-[(2R,4S,5R)-5-[({[(1-carboxylato-2-oxo-2-phenylethyl)amino]phosphinato}oxy)methyl]-3,4-bis(propan-2-yloxy)oxolan-2-yl]-6-hydroxy-9H-purin-7-ium

SMILES: CC(C)O[C@H]1[C@@H](COP([O-])(=O)NC(C([O-])=O)C(=O)c2ccccc2)O[C@H](C1OC(C)C)n1c[nH+]c2c1nc(N)[nH]c2=O

InChI Key: InChIKey=KRYBNXLEOXPKTJ-KPRHEIOISA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50165135 (CHEMBL193790 | disodium 2-amino-9-[(2R,4S,5R)-5-[(...) Show SMILES CC(C)O[C@H]1[C@@H](COP([O-])(=O)NC(C([O-])=O)C(=O)c2ccccc2)O[C@H](C1OC(C)C)n1c[nH+]c2c1nc(N)[nH]c2=O Show InChI InChI=1S/C25H33N6O10P/c1-12(2)39-19-15(10-38-42(36,37)30-16(24(34)35)18(32)14-8-6-5-7-9-14)41-23(20(19)40-13(3)4)31-11-27-17-21(31)28-25(26)29-22(17)33/h5-9,11-13,15-16,19-20,23H,10H2,1-4H3,(H,34,35)(H2,30,36,37)(H3,26,28,29,33)/p-1/t15-,16?,19+,20?,23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair