BDBM50165489 4-(3-(2-oxopyrrolidin-1-yl)benzyl)phthalazin-1(2H)-one::4-[3-(2-Oxo-pyrrolidin-1-yl)-benzyl]-2H-phthalazin-1-one::CHEMBL196559

SMILES: O=C1CCCN1c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=GJMJJWLKXRWMKJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50165489 (4-(3-(2-oxopyrrolidin-1-yl)benzyl)phthalazin-1(2H)...) Show SMILES O=C1CCCN1c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C19H17N3O2/c23-18-9-4-10-22(18)14-6-3-5-13(11-14)12-17-15-7-1-2-8-16(15)19(24)21-20-17/h1-3,5-8,11H,4,9-10,12H2,(H,21,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant PARP1				J Med Chem 52: 718-25 (2009) Article DOI: 10.1021/jm800902t BindingDB Entry DOI: 10.7270/Q2C53KPW
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50165489 (4-(3-(2-oxopyrrolidin-1-yl)benzyl)phthalazin-1(2H)...) Show SMILES O=C1CCCN1c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C19H17N3O2/c23-18-9-4-10-22(18)14-6-3-5-13(11-14)12-17-15-7-1-2-8-16(15)19(24)21-20-17/h1-3,5-8,11H,4,9-10,12H2,(H,21,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Horsham Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)				Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B
					More data for this Ligand-Target Pair