null

SMILES: CSc1sc(-c2cc[nH]n2)c2[C@@H](C)CNC(=O)c12

InChI Key: InChIKey=HJNQBCIFYVLKQF-LURJTMIESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50166014 (CHEMBL3798802) Show SMILES CSc1sc(-c2cc[nH]n2)c2[C@@H](C)CNC(=O)c12 |r| Show InChI InChI=1S/C12H13N3OS2/c1-6-5-13-11(16)9-8(6)10(18-12(9)17-2)7-3-4-14-15-7/h3-4,6H,5H2,1-2H3,(H,13,16)(H,14,15)/t6-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant LRRK2 G2019S mutant using fluorescein- ERM as substrate after 1 hr by TR-FRET assay				Bioorg Med Chem Lett 26: 2631-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.021 BindingDB Entry DOI: 10.7270/Q2RV0QKC
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50166014 (CHEMBL3798802) Show SMILES CSc1sc(-c2cc[nH]n2)c2[C@@H](C)CNC(=O)c12 |r| Show InChI InChI=1S/C12H13N3OS2/c1-6-5-13-11(16)9-8(6)10(18-12(9)17-2)7-3-4-14-15-7/h3-4,6H,5H2,1-2H3,(H,13,16)(H,14,15)/t6-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	319	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant wild type LRRK2 using fluorescein- ERM as substrate after 1 hr by TR-FRET assay				Bioorg Med Chem Lett 26: 2631-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.021 BindingDB Entry DOI: 10.7270/Q2RV0QKC
					More data for this Ligand-Target Pair