BDBM50166074 CHEMBL3797308

SMILES: COCC1Cc2c(sc(SC)c2C(=O)N1)-c1cc[nH]n1

InChI Key: InChIKey=UHDYVWQTUFNUMX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50166074 (CHEMBL3797308) Show SMILES COCC1Cc2c(sc(SC)c2C(=O)N1)-c1cc[nH]n1 Show InChI InChI=1S/C13H15N3O2S2/c1-18-6-7-5-8-10(12(17)15-7)13(19-2)20-11(8)9-3-4-14-16-9/h3-4,7H,5-6H2,1-2H3,(H,14,16)(H,15,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	341	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant LRRK2 G2019S mutant using fluorescein- ERM as substrate after 1 hr by TR-FRET assay				Bioorg Med Chem Lett 26: 2631-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.021 BindingDB Entry DOI: 10.7270/Q2RV0QKC
					More data for this Ligand-Target Pair