BDBM50166308 (S)-1-[(2S,4S)-4-(4-Nitro-phenylamino)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile::CHEMBL370540
SMILES: [O-][N+](=O)c1ccc(N[C@@H]2CN[C@@H](C2)C(=O)N2CCC[C@H]2C#N)cc1
InChI Key: InChIKey=QMIDPCJVTGIENJ-QEJZJMRPSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50166308 ((S)-1-[(2S,4S)-4-(4-Nitro-phenylamino)-pyrrolidine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Inhibitory concentration against human dipeptidyl-peptidase IV | Bioorg Med Chem Lett 15: 2441-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase IV (Rattus norvegicus (rat)) | BDBM50166308 ((S)-1-[(2S,4S)-4-(4-Nitro-phenylamino)-pyrrolidine...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Inhibitory concentration against rat dipeptidyl-peptidase IV | Bioorg Med Chem Lett 15: 2441-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ | |||||||||||
More data for this Ligand-Target Pair |