BDBM50166317 (S)-1-[(2S,4S)-4-(4-Methoxy-phenylamino)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile::CHEMBL195063

SMILES: COc1ccc(N[C@@H]2CN[C@@H](C2)C(=O)N2CCC[C@H]2C#N)cc1

InChI Key: InChIKey=MELTZFMVXJTYAK-DZKIICNBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase IV (Rattus norvegicus (rat))	BDBM50166317 ((S)-1-[(2S,4S)-4-(4-Methoxy-phenylamino)-pyrrolidi...) Show SMILES COc1ccc(N[C@@H]2CN[C@@H](C2)C(=O)N2CCC[C@H]2C#N)cc1 Show InChI InChI=1S/C17H22N4O2/c1-23-15-6-4-12(5-7-15)20-13-9-16(19-11-13)17(22)21-8-2-3-14(21)10-18/h4-7,13-14,16,19-20H,2-3,8-9,11H2,1H3/t13-,14-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibitory concentration against rat dipeptidyl-peptidase IV				Bioorg Med Chem Lett 15: 2441-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50166317 ((S)-1-[(2S,4S)-4-(4-Methoxy-phenylamino)-pyrrolidi...) Show SMILES COc1ccc(N[C@@H]2CN[C@@H](C2)C(=O)N2CCC[C@H]2C#N)cc1 Show InChI InChI=1S/C17H22N4O2/c1-23-15-6-4-12(5-7-15)20-13-9-16(19-11-13)17(22)21-8-2-3-14(21)10-18/h4-7,13-14,16,19-20H,2-3,8-9,11H2,1H3/t13-,14-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Inhibitory concentration against human dipeptidyl-peptidase IV				Bioorg Med Chem Lett 15: 2441-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.077 BindingDB Entry DOI: 10.7270/Q27P8XWJ
					More data for this Ligand-Target Pair