BDBM50166427 CHEMBL3798015

SMILES: Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)C(=O)NC(CO)c1cccc(Cl)c1

InChI Key: InChIKey=OMKSHRGIEVKCAP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM50166427 (CHEMBL3798015) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)C(=O)NC(CO)c1cccc(Cl)c1 Show InChI InChI=1S/C22H19ClN4O2/c1-13-9-15(7-8-24-13)21-18-11-16(5-6-19(18)26-27-21)22(29)25-20(12-28)14-3-2-4-17(23)10-14/h2-11,20,28H,12H2,1H3,(H,25,29)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Green Valley Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged ERK1 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...				Bioorg Med Chem Lett 26: 2600-4 (2016) Article DOI: 10.1016/j.bmcl.2016.04.029 BindingDB Entry DOI: 10.7270/Q2H99731
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50166427 (CHEMBL3798015) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)C(=O)NC(CO)c1cccc(Cl)c1 Show InChI InChI=1S/C22H19ClN4O2/c1-13-9-15(7-8-24-13)21-18-11-16(5-6-19(18)26-27-21)22(29)25-20(12-28)14-3-2-4-17(23)10-14/h2-11,20,28H,12H2,1H3,(H,25,29)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Green Valley Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged ERK2 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...				Bioorg Med Chem Lett 26: 2600-4 (2016) Article DOI: 10.1016/j.bmcl.2016.04.029 BindingDB Entry DOI: 10.7270/Q2H99731
					More data for this Ligand-Target Pair