BDBM50166508 2-(2-Hydroxy-phenyl)-3-phenethyl-3,4a,5,6,7,7a-hexahydro-cyclopentapyrimidin-4-one::CHEMBL370503

SMILES: Oc1ccccc1C1=NC2CCCC2C(=O)N1CCc1ccccc1

InChI Key: InChIKey=MDOFCYYTJTYMQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50166508 (2-(2-Hydroxy-phenyl)-3-phenethyl-3,4a,5,6,7,7a-hex...) Show SMILES Oc1ccccc1C1=NC2CCCC2C(=O)N1CCc1ccccc1 |t:8| Show InChI InChI=1S/C21H22N2O2/c24-19-12-5-4-9-17(19)20-22-18-11-6-10-16(18)21(25)23(20)14-13-15-7-2-1-3-8-15/h1-5,7-9,12,16,18,24H,6,10-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair