BDBM50166509 3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)-3,4a,5,6,7,7a-hexahydro-cyclopentapyrimidin-4-one::CHEMBL195375

SMILES: Oc1ccccc1C1=NC2CCCC2C(=O)N1CCc1cccc(F)c1

InChI Key: InChIKey=RVUYYDYEDLCXFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50166509 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Oc1ccccc1C1=NC2CCCC2C(=O)N1CCc1cccc(F)c1 |t:8| Show InChI InChI=1S/C21H21FN2O2/c22-15-6-3-5-14(13-15)11-12-24-20(17-7-1-2-10-19(17)25)23-18-9-4-8-16(18)21(24)26/h1-3,5-7,10,13,16,18,25H,4,8-9,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor				Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ
					More data for this Ligand-Target Pair