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SMILES: C[C@@H](NC(=O)c1ccc2[nH]nc(-c3ccnc(C)c3)c2c1)c1c(Cl)cccc1Cl

InChI Key: InChIKey=SVZFHBDBECKIKZ-CYBMUJFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166570   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (Human))		BDBM50166570
PNG
(CHEMBL3798401)
Show SMILES C[C@@H](NC(=O)c1ccc2[nH]nc(-c3ccnc(C)c3)c2c1)c1c(Cl)cccc1Cl |r|
Show InChI InChI=1S/C22H18Cl2N4O/c1-12-10-14(8-9-25-12)21-16-11-15(6-7-19(16)27-28-21)22(29)26-13(2)20-17(23)4-3-5-18(20)24/h3-11,13H,1-2H3,(H,26,29)(H,27,28)/t13-/m1/s1
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Similars
Article
PubMed
n/an/a 632n/an/an/an/an/an/a



Green Valley Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged ERK2 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...

Bioorg Med Chem Lett 26: 2600-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.029
BindingDB Entry DOI: 10.7270/Q2H99731
More data for this
Ligand-Target Pair