BDBM50166581 CHEMBL3797387

SMILES: CCn1ncc2c(F)cc(cc12)C(=O)Nc1nnc(s1)C1CC1

InChI Key: InChIKey=NFPDJHLZKGIIED-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50166581 (CHEMBL3797387) Show SMILES CCn1ncc2c(F)cc(cc12)C(=O)Nc1nnc(s1)C1CC1 Show InChI InChI=1S/C15H14FN5OS/c1-2-21-12-6-9(5-11(16)10(12)7-17-21)13(22)18-15-20-19-14(23-15)8-3-4-8/h5-8H,2-4H2,1H3,(H,18,20,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in human Chem1 cell membrane by scintillation proximity assay				Bioorg Med Chem Lett 26: 2670-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.009 BindingDB Entry DOI: 10.7270/Q2CJ8GDR
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50166581 (CHEMBL3797387) Show SMILES CCn1ncc2c(F)cc(cc12)C(=O)Nc1nnc(s1)C1CC1 Show InChI InChI=1S/C15H14FN5OS/c1-2-21-12-6-9(5-11(16)10(12)7-17-21)13(22)18-15-20-19-14(23-15)8-3-4-8/h5-8H,2-4H2,1H3,(H,18,20,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant EP3 receptor expressed in CHOK1 cells assessed as inhibition of sulprostone-induced decrease in cAMP level p...				Bioorg Med Chem Lett 26: 2670-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.009 BindingDB Entry DOI: 10.7270/Q2CJ8GDR
					More data for this Ligand-Target Pair