BDBM50166598 CHEMBL3799237

SMILES: CCN1c2cc(ccc2C(=O)NC1(C)C)-c1c(C)n[nH]c1C

InChI Key: InChIKey=DUTODZZHAPKLHS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50166598 (CHEMBL3799237) Show SMILES CCN1c2cc(ccc2C(=O)NC1(C)C)-c1c(C)n[nH]c1C Show InChI InChI=1S/C17H22N4O/c1-6-21-14-9-12(15-10(2)19-20-11(15)3)7-8-13(14)16(22)18-17(21,4)5/h7-9H,6H2,1-5H3,(H,18,22)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...				Bioorg Med Chem 24: 2466-75 (2016) Article DOI: 10.1016/j.bmc.2016.04.008 BindingDB Entry DOI: 10.7270/Q27W6F29
					More data for this Ligand-Target Pair