BDBM50166841 CHEMBL3800190

SMILES: CCN1CCN(CC1)c1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)nc(NCc3cc(C)no3)nc2c1

InChI Key: InChIKey=FQWFCEMZVYHRRW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50166841 (CHEMBL3800190) Show SMILES CCN1CCN(CC1)c1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)nc(NCc3cc(C)no3)nc2c1 Show InChI InChI=1S/C32H39N9O3/c1-5-40-10-12-41(13-11-40)24-8-9-28-29(18-24)34-32(33-20-27-14-21(2)39-44-27)36-31(28)35-30-17-23(37-38-30)7-6-22-15-25(42-3)19-26(16-22)43-4/h8-9,14-19H,5-7,10-13,20H2,1-4H3,(H3,33,34,35,36,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assay				Bioorg Med Chem Lett 26: 2594-9 (2016) Article DOI: 10.1016/j.bmcl.2016.04.028 BindingDB Entry DOI: 10.7270/Q20C4XNM
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50166841 (CHEMBL3800190) Show SMILES CCN1CCN(CC1)c1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)nc(NCc3cc(C)no3)nc2c1 Show InChI InChI=1S/C32H39N9O3/c1-5-40-10-12-41(13-11-40)24-8-9-28-29(18-24)34-32(33-20-27-14-21(2)39-44-27)36-31(28)35-30-17-23(37-38-30)7-6-22-15-25(42-3)19-26(16-22)43-4/h8-9,14-19H,5-7,10-13,20H2,1-4H3,(H3,33,34,35,36,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA				Bioorg Med Chem Lett 26: 2594-9 (2016) Article DOI: 10.1016/j.bmcl.2016.04.028 BindingDB Entry DOI: 10.7270/Q20C4XNM
					More data for this Ligand-Target Pair