BDBM50167310 1-((E)-3-Benzo[b]thiophen-2-yl-allyl)-5-iodo-1H-indole-2,3-dione::CHEMBL188983

SMILES: Ic1ccc2N(C\C=C\c3cc4ccccc4s3)C(=O)C(=O)c2c1

InChI Key: InChIKey=ULTYNOLOPCCXGD-HWKANZROSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM50167310 (1-((E)-3-Benzo[b]thiophen-2-yl-allyl)-5-iodo-1H-in...) Show SMILES Ic1ccc2N(C\C=C\c3cc4ccccc4s3)C(=O)C(=O)c2c1 Show InChI InChI=1S/C19H12INO2S/c20-13-7-8-16-15(11-13)18(22)19(23)21(16)9-3-5-14-10-12-4-1-2-6-17(12)24-14/h1-8,10-11H,9H2/b5-3+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Papain-like protease (PLpro) (Human SARS coronavirus (SARS-CoV))	BDBM50167310 (1-((E)-3-Benzo[b]thiophen-2-yl-allyl)-5-iodo-1H-in...) Show SMILES Ic1ccc2N(C\C=C\c3cc4ccccc4s3)C(=O)C(=O)c2c1 Show InChI InChI=1S/C19H12INO2S/c20-13-7-8-16-15(11-13)18(22)19(23)21(16)9-3-5-14-10-12-4-1-2-6-17(12)24-14/h1-8,10-11H,9H2/b5-3+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Development Center for Biotechnology Curated by ChEMBL					Assay Description In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)				Bioorg Med Chem Lett 15: 3058-62 (2005) Article DOI: 10.1016/j.bmcl.2005.04.027 BindingDB Entry DOI: 10.7270/Q2H131JB
					More data for this Ligand-Target Pair