BDBM50167315 5-Iodo-1-[5-(piperidine-1-carbonyl)-thiophen-2-ylmethyl]-1H-indole-2,3-dione::CHEMBL370923

SMILES: Ic1ccc2N(Cc3ccc(s3)C(=O)N3CCCCC3)C(=O)C(=O)c2c1

InChI Key: InChIKey=FJXCZSNZFQISSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3C-like proteinase (3CL-PRO) (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM50167315 (5-Iodo-1-[5-(piperidine-1-carbonyl)-thiophen-2-ylm...) Show SMILES Ic1ccc2N(Cc3ccc(s3)C(=O)N3CCCCC3)C(=O)C(=O)c2c1 Show InChI InChI=1S/C19H17IN2O3S/c20-12-4-6-15-14(10-12)17(23)19(25)22(15)11-13-5-7-16(26-13)18(24)21-8-2-1-3-9-21/h4-7,10H,1-3,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Papain-like protease (PLpro) (Human SARS coronavirus (SARS-CoV))	BDBM50167315 (5-Iodo-1-[5-(piperidine-1-carbonyl)-thiophen-2-ylm...) Show SMILES Ic1ccc2N(Cc3ccc(s3)C(=O)N3CCCCC3)C(=O)C(=O)c2c1 Show InChI InChI=1S/C19H17IN2O3S/c20-12-4-6-15-14(10-12)17(23)19(25)22(15)11-13-5-7-16(26-13)18(24)21-8-2-1-3-9-21/h4-7,10H,1-3,8-9,11H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Development Center for Biotechnology Curated by ChEMBL					Assay Description In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)				Bioorg Med Chem Lett 15: 3058-62 (2005) Article DOI: 10.1016/j.bmcl.2005.04.027 BindingDB Entry DOI: 10.7270/Q2H131JB
					More data for this Ligand-Target Pair