BDBM50167395 CHEMBL3799737

SMILES: N[C@@H](Cc1ccc(cc1)C(=O)\N=C(/N)NCc1c(Oc2ccccc2Cl)cccc1N1CCCCC1)C(O)=O

InChI Key: InChIKey=OGXYQCYGWXTRGN-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50167395 (CHEMBL3799737) Show SMILES N[C@@H](Cc1ccc(cc1)C(=O)\N=C(/N)NCc1c(Oc2ccccc2Cl)cccc1N1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C29H32ClN5O4/c30-22-7-2-3-9-26(22)39-25-10-6-8-24(35-15-4-1-5-16-35)21(25)18-33-29(32)34-27(36)20-13-11-19(12-14-20)17-23(31)28(37)38/h2-3,6-14,23H,1,4-5,15-18,31H2,(H,37,38)(H3,32,33,34,36)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 26: 2855-2860 (2016) Article DOI: 10.1016/j.bmcl.2016.04.057 BindingDB Entry DOI: 10.7270/Q2SN0BW3
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