Found 5 hits for monomerid = 50167406 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50167406
(4-(2-((4-oxo-4H-chromen-3-yl)methyleneamino)ethyl)...)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C18H16N2O4S/c19-25(22,23)15-7-5-13(6-8-15)9-10-20-11-14-12-24-17-4-2-1-3-16(17)18(14)21/h1-8,11-12H,9-10H2,(H2,19,22,23)/b20-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ospedale San Lazzaro
Curated by ChEMBL
| Assay Description Inhibition constant against human carbonic anhydrase II |
Bioorg Med Chem Lett 15: 3096-101 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50167406
(4-(2-((4-oxo-4H-chromen-3-yl)methyleneamino)ethyl)...)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C18H16N2O4S/c19-25(22,23)15-7-5-13(6-8-15)9-10-20-11-14-12-24-17-4-2-1-3-16(17)18(14)21/h1-8,11-12H,9-10H2,(H2,19,22,23)/b20-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ospedale San Lazzaro
Curated by ChEMBL
| Assay Description Inhibition constant against human carbonic anhydrase IX |
Bioorg Med Chem Lett 15: 3096-101 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50167406
(4-(2-((4-oxo-4H-chromen-3-yl)methyleneamino)ethyl)...)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C18H16N2O4S/c19-25(22,23)15-7-5-13(6-8-15)9-10-20-11-14-12-24-17-4-2-1-3-16(17)18(14)21/h1-8,11-12H,9-10H2,(H2,19,22,23)/b20-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ospedale San Lazzaro
Curated by ChEMBL
| Assay Description Inhibition constant against human carbonic anhydrase XII |
Bioorg Med Chem Lett 15: 3096-101 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50167406
(4-(2-((4-oxo-4H-chromen-3-yl)methyleneamino)ethyl)...)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C18H16N2O4S/c19-25(22,23)15-7-5-13(6-8-15)9-10-20-11-14-12-24-17-4-2-1-3-16(17)18(14)21/h1-8,11-12H,9-10H2,(H2,19,22,23)/b20-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ospedale San Lazzaro
Curated by ChEMBL
| Assay Description Inhibition constant against human carbonic anhydrase I |
Bioorg Med Chem Lett 15: 3096-101 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50167406
(4-(2-((4-oxo-4H-chromen-3-yl)methyleneamino)ethyl)...)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C18H16N2O4S/c19-25(22,23)15-7-5-13(6-8-15)9-10-20-11-14-12-24-17-4-2-1-3-16(17)18(14)21/h1-8,11-12H,9-10H2,(H2,19,22,23)/b20-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10E+10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harran University
Curated by ChEMBL
| Assay Description Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydration |
Eur J Med Chem 44: 3439-44 (2009)
Article DOI: 10.1016/j.ejmech.2009.02.016 BindingDB Entry DOI: 10.7270/Q26W9DWG |
More data for this Ligand-Target Pair | |