BDBM50167416 4-(((6-methyl-4-oxo-4H-chromen-3-yl)methyleneamino)methyl)benzenesulfonamide::4-({[1-(6-Methyl-4-oxo-4H-chromen-3-yl)-meth-(E)-ylidene]-amino}-methyl)-benzenesulfonamide::CHEMBL193907

SMILES: Cc1ccc2occ(\C=N\Cc3ccc(cc3)S(N)(=O)=O)c(=O)c2c1

InChI Key: InChIKey=QVCVIBPFAGHIDX-KEBDBYFISA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50167416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50167416 (4-(((6-methyl-4-oxo-4H-chromen-3-yl)methyleneamino...) Show SMILES Cc1ccc2occ(\C=N\Cc3ccc(cc3)S(N)(=O)=O)c(=O)c2c1 Show InChI InChI=1S/C18H16N2O4S/c1-12-2-7-17-16(8-12)18(21)14(11-24-17)10-20-9-13-3-5-15(6-4-13)25(19,22)23/h2-8,10-11H,9H2,1H3,(H2,19,22,23)/b20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase I				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50167416 (4-(((6-methyl-4-oxo-4H-chromen-3-yl)methyleneamino...) Show SMILES Cc1ccc2occ(\C=N\Cc3ccc(cc3)S(N)(=O)=O)c(=O)c2c1 Show InChI InChI=1S/C18H16N2O4S/c1-12-2-7-17-16(8-12)18(21)14(11-24-17)10-20-9-13-3-5-15(6-4-13)25(19,22)23/h2-8,10-11H,9H2,1H3,(H2,19,22,23)/b20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase IX				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50167416 (4-(((6-methyl-4-oxo-4H-chromen-3-yl)methyleneamino...) Show SMILES Cc1ccc2occ(\C=N\Cc3ccc(cc3)S(N)(=O)=O)c(=O)c2c1 Show InChI InChI=1S/C18H16N2O4S/c1-12-2-7-17-16(8-12)18(21)14(11-24-17)10-20-9-13-3-5-15(6-4-13)25(19,22)23/h2-8,10-11H,9H2,1H3,(H2,19,22,23)/b20-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase XII				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50167416 (4-(((6-methyl-4-oxo-4H-chromen-3-yl)methyleneamino...) Show SMILES Cc1ccc2occ(\C=N\Cc3ccc(cc3)S(N)(=O)=O)c(=O)c2c1 Show InChI InChI=1S/C18H16N2O4S/c1-12-2-7-17-16(8-12)18(21)14(11-24-17)10-20-9-13-3-5-15(6-4-13)25(19,22)23/h2-8,10-11H,9H2,1H3,(H2,19,22,23)/b20-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ospedale San Lazzaro Curated by ChEMBL					Assay Description Inhibition constant against human carbonic anhydrase II				Bioorg Med Chem Lett 15: 3096-101 (2005) Article DOI: 10.1016/j.bmcl.2005.04.055 BindingDB Entry DOI: 10.7270/Q27M07FQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50167416 (4-(((6-methyl-4-oxo-4H-chromen-3-yl)methyleneamino...) Show SMILES Cc1ccc2occ(\C=N\Cc3ccc(cc3)S(N)(=O)=O)c(=O)c2c1 Show InChI InChI=1S/C18H16N2O4S/c1-12-2-7-17-16(8-12)18(21)14(11-24-17)10-20-9-13-3-5-15(6-4-13)25(19,22)23/h2-8,10-11H,9H2,1H3,(H2,19,22,23)/b20-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harran University Curated by ChEMBL					Assay Description Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydration				Eur J Med Chem 44: 3439-44 (2009) Article DOI: 10.1016/j.ejmech.2009.02.016 BindingDB Entry DOI: 10.7270/Q26W9DWG
					More data for this Ligand-Target Pair