BDBM50167438 CHEMBL191464::Quinoline-6-carboxylic acid [1'-(3,4-dichloro-benzyl)-3'-methyl-[1,4']bipiperidinyl-3-ylmethyl]-amide

SMILES: CC1CN(Cc2ccc(Cl)c(Cl)c2)CCC1N1CCCC(CNC(=O)c2ccc3ncccc3c2)C1

InChI Key: InChIKey=RPJZHDKOKSGFON-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50167438 (CHEMBL191464 | Quinoline-6-carboxylic acid [1'-(3,...) Show SMILES CC1CN(Cc2ccc(Cl)c(Cl)c2)CCC1N1CCCC(CNC(=O)c2ccc3ncccc3c2)C1 Show InChI InChI=1S/C29H34Cl2N4O/c1-20-17-34(18-21-6-8-25(30)26(31)14-21)13-10-28(20)35-12-3-4-22(19-35)16-33-29(36)24-7-9-27-23(15-24)5-2-11-32-27/h2,5-9,11,14-15,20,22,28H,3-4,10,12-13,16-19H2,1H3,(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding activity against C-C chemokine receptor type 3 using [35S]-GTP-gammaS, as radioligand				Bioorg Med Chem Lett 15: 3020-3 (2005) Article DOI: 10.1016/j.bmcl.2005.04.054 BindingDB Entry DOI: 10.7270/Q23T9GRW
					More data for this Ligand-Target Pair