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SMILES: N[C@@H](Cc1ccc(cc1)C(=O)\N=C(/N)NCc1cc(Cl)ccc1N1CCCCC1)C(O)=O

InChI Key: InChIKey=DTYVLCGPSMKXJD-IBGZPJMESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167508   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))		BDBM50167508
PNG
(CHEMBL3797520)
Show SMILES N[C@@H](Cc1ccc(cc1)C(=O)\N=C(/N)NCc1cc(Cl)ccc1N1CCCCC1)C(O)=O |r|
Show InChI InChI=1S/C23H28ClN5O3/c24-18-8-9-20(29-10-2-1-3-11-29)17(13-18)14-27-23(26)28-21(30)16-6-4-15(5-7-16)12-19(25)22(31)32/h4-9,13,19H,1-3,10-12,14,25H2,(H,31,32)(H3,26,27,28,30)/t19-/m0/s1
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n/an/a 16n/an/an/an/an/an/a



Karos Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of TPH1 (unknown origin)

Bioorg Med Chem Lett 26: 2855-2860 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.057
BindingDB Entry DOI: 10.7270/Q2SN0BW3
More data for this
Ligand-Target Pair