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BDBM50167536 CHEMBL3799767

SMILES: Cc1cccc(N2CCCCC2)c1CN\C(N)=N\C(=O)c1ccc(C[C@H](N)C(O)=O)cc1

InChI Key: InChIKey=LRHBSDSLQKVIES-GNLPSFAGNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167536   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))
BDBM50167536
PNG
(CHEMBL3799767)
Show SMILES Cc1cccc(N2CCCCC2)c1CN\C(N)=N\C(=O)c1ccc(C[C@H](N)C(O)=O)cc1 |r|
Show InChI InChI=1/C24H31N5O3/c1-16-6-5-7-21(29-12-3-2-4-13-29)19(16)15-27-24(26)28-22(30)18-10-8-17(9-11-18)14-20(25)23(31)32/h5-11,20H,2-4,12-15,25H2,1H3,(H,31,32)(H3,26,27,28,30)/t20-/s2
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MMDB

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PubMed
n/an/a 12n/an/an/an/an/an/a



Karos Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of TPH1 (unknown origin)


Bioorg Med Chem Lett 26: 2855-2860 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.057
BindingDB Entry DOI: 10.7270/Q2SN0BW3
More data for this
Ligand-Target Pair