BDBM50167552 1-[1-(2-Cyclopentylamino-ethyl)-1H-indazol-5-yl]-3-(4-phenoxy-phenyl)-urea::CHEMBL196599

SMILES: O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2n(CCNC3CCCC3)ncc2c1

InChI Key: InChIKey=JGSWRBZQDGUIET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50167552 (1-[1-(2-Cyclopentylamino-ethyl)-1H-indazol-5-yl]-3...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2n(CCNC3CCCC3)ncc2c1 Show InChI InChI=1S/C27H29N5O2/c33-27(30-22-10-13-25(14-11-22)34-24-8-2-1-3-9-24)31-23-12-15-26-20(18-23)19-29-32(26)17-16-28-21-6-4-5-7-21/h1-3,8-15,18-19,21,28H,4-7,16-17H2,(H2,30,31,33)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCH				Bioorg Med Chem Lett 15: 2752-7 (2005) Article DOI: 10.1016/j.bmcl.2005.03.114 BindingDB Entry DOI: 10.7270/Q2QJ7GSD
					More data for this Ligand-Target Pair