BDBM50167891 CHEMBL197319::{6-[(Diphenylcarbamoyloxy)-methyl]-5,6,7,8-tetrahydro-naphthalen-1-yloxy}-acetic acid

SMILES: OC(=O)COc1cccc2CC(COC(=O)N(c3ccccc3)c3ccccc3)CCc12

InChI Key: InChIKey=CDAMGZXJUYMJLP-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50167891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50167891 (CHEMBL197319 | {6-[(Diphenylcarbamoyloxy)-methyl]-...) Show SMILES OC(=O)COc1cccc2CC(COC(=O)N(c3ccccc3)c3ccccc3)CCc12 Show InChI InChI=1S/C26H25NO5/c28-25(29)18-31-24-13-7-8-20-16-19(14-15-23(20)24)17-32-26(30)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-13,19H,14-18H2,(H,28,29)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]iloprost from human Prostanoid IP receptor				Bioorg Med Chem Lett 15: 3091-5 (2005) Article DOI: 10.1016/j.bmcl.2005.04.047 BindingDB Entry DOI: 10.7270/Q2SF2WXV
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50167891 (CHEMBL197319 | {6-[(Diphenylcarbamoyloxy)-methyl]-...) Show SMILES OC(=O)COc1cccc2CC(COC(=O)N(c3ccccc3)c3ccccc3)CCc12 Show InChI InChI=1S/C26H25NO5/c28-25(29)18-31-24-13-7-8-20-16-19(14-15-23(20)24)17-32-26(30)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-13,19H,14-18H2,(H,28,29)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]PGE-2 from human Prostanoid EP1 receptor				Bioorg Med Chem Lett 15: 3091-5 (2005) Article DOI: 10.1016/j.bmcl.2005.04.047 BindingDB Entry DOI: 10.7270/Q2SF2WXV
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50167891 (CHEMBL197319 | {6-[(Diphenylcarbamoyloxy)-methyl]-...) Show SMILES OC(=O)COc1cccc2CC(COC(=O)N(c3ccccc3)c3ccccc3)CCc12 Show InChI InChI=1S/C26H25NO5/c28-25(29)18-31-24-13-7-8-20-16-19(14-15-23(20)24)17-32-26(30)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-13,19H,14-18H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE-2 from human Prostanoid EP2 receptor				Bioorg Med Chem Lett 15: 3091-5 (2005) Article DOI: 10.1016/j.bmcl.2005.04.047 BindingDB Entry DOI: 10.7270/Q2SF2WXV
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50167891 (CHEMBL197319 | {6-[(Diphenylcarbamoyloxy)-methyl]-...) Show SMILES OC(=O)COc1cccc2CC(COC(=O)N(c3ccccc3)c3ccccc3)CCc12 Show InChI InChI=1S/C26H25NO5/c28-25(29)18-31-24-13-7-8-20-16-19(14-15-23(20)24)17-32-26(30)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-13,19H,14-18H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]PGE-2 from human Prostanoid EP3 receptor				Bioorg Med Chem Lett 15: 3091-5 (2005) Article DOI: 10.1016/j.bmcl.2005.04.047 BindingDB Entry DOI: 10.7270/Q2SF2WXV
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50167891 (CHEMBL197319 | {6-[(Diphenylcarbamoyloxy)-methyl]-...) Show SMILES OC(=O)COc1cccc2CC(COC(=O)N(c3ccccc3)c3ccccc3)CCc12 Show InChI InChI=1S/C26H25NO5/c28-25(29)18-31-24-13-7-8-20-16-19(14-15-23(20)24)17-32-26(30)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-13,19H,14-18H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]PGE-2 from human Prostanoid EP4 receptor				Bioorg Med Chem Lett 15: 3091-5 (2005) Article DOI: 10.1016/j.bmcl.2005.04.047 BindingDB Entry DOI: 10.7270/Q2SF2WXV
					More data for this Ligand-Target Pair