BDBM50168170 3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol-2-yl]-piperidin-1-yl}-propylamine::CHEMBL370263

SMILES: NCCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=VOPOULRVLGISBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50168170 (3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...) Show SMILES NCCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H27FN4/c24-20-4-2-19(3-5-20)23-21(17-6-11-26-12-7-17)16-22(27-23)18-8-14-28(15-9-18)13-1-10-25/h2-7,11-12,16,18,27H,1,8-10,13-15,25H2	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0460	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase				Bioorg Med Chem Lett 15: 3296-301 (2005) Article DOI: 10.1016/j.bmcl.2005.04.060 BindingDB Entry DOI: 10.7270/Q24M9421
					More data for this Ligand-Target Pair