BDBM50168333 6-(2,6-Difluoro-4-hydroxy-phenyl)-naphthalen-2-ol::CHEMBL192621
SMILES: Oc1ccc2cc(ccc2c1)-c1c(F)cc(O)cc1F
InChI Key: InChIKey=AUZLISXBMGKYGA-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM50168333 (6-(2,6-Difluoro-4-hydroxy-phenyl)-naphthalen-2-ol ...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coli | J Med Chem 48: 3953-79 (2005) Article DOI: 10.1021/jm058173s BindingDB Entry DOI: 10.7270/Q2QF8SF0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50168333 (6-(2,6-Difluoro-4-hydroxy-phenyl)-naphthalen-2-ol ...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor alpha expressed in Escherichia coli | J Med Chem 48: 3953-79 (2005) Article DOI: 10.1021/jm058173s BindingDB Entry DOI: 10.7270/Q2QF8SF0 | |||||||||||
More data for this Ligand-Target Pair |