BDBM50168352 4-Ethynyl-6-(3-fluoro-4-hydroxy-phenyl)-naphthalen-2-ol::CHEMBL191759

SMILES: Oc1cc(C#C)c2cc(ccc2c1)-c1ccc(O)c(F)c1

InChI Key: InChIKey=UCTPVBCFMDURFZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50168352 (4-Ethynyl-6-(3-fluoro-4-hydroxy-phenyl)-naphthalen...) Show SMILES Oc1cc(C#C)c2cc(ccc2c1)-c1ccc(O)c(F)c1 Show InChI InChI=1S/C18H11FO2/c1-2-11-7-15(20)8-14-4-3-12(9-16(11)14)13-5-6-18(21)17(19)10-13/h1,3-10,20-21H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor alpha expressed in Escherichia coli				J Med Chem 48: 3953-79 (2005) Article DOI: 10.1021/jm058173s BindingDB Entry DOI: 10.7270/Q2QF8SF0
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50168352 (4-Ethynyl-6-(3-fluoro-4-hydroxy-phenyl)-naphthalen...) Show SMILES Oc1cc(C#C)c2cc(ccc2c1)-c1ccc(O)c(F)c1 Show InChI InChI=1S/C18H11FO2/c1-2-11-7-15(20)8-14-4-3-12(9-16(11)14)13-5-6-18(21)17(19)10-13/h1,3-10,20-21H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coli				J Med Chem 48: 3953-79 (2005) Article DOI: 10.1021/jm058173s BindingDB Entry DOI: 10.7270/Q2QF8SF0
					More data for this Ligand-Target Pair