BDBM50168413 5-Isopropyl-4-(3-methoxycarbamoyl-phenylamino)-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester::CHEMBL365178::ethyl 5-isopropyl-4-(3-(methoxycarbamoyl)phenylamino)pyrrolo[1,2-f][1,2,4]triazine-6-carboxylate

SMILES: CCOC(=O)c1cn2ncnc(Nc3cccc(c3)C(=O)NOC)c2c1C(C)C

InChI Key: InChIKey=LURXYGPJYWRADP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168413 (5-Isopropyl-4-(3-methoxycarbamoyl-phenylamino)-pyr...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3cccc(c3)C(=O)NOC)c2c1C(C)C Show InChI InChI=1S/C20H23N5O4/c1-5-29-20(27)15-10-25-17(16(15)12(2)3)18(21-11-22-25)23-14-8-6-7-13(9-14)19(26)24-28-4/h6-12H,5H2,1-4H3,(H,24,26)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiaotong University Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 2126-33 (2007) Article DOI: 10.1016/j.bmcl.2007.01.089 BindingDB Entry DOI: 10.7270/Q2S1839D
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50168413 (5-Isopropyl-4-(3-methoxycarbamoyl-phenylamino)-pyr...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3cccc(c3)C(=O)NOC)c2c1C(C)C Show InChI InChI=1S/C20H23N5O4/c1-5-29-20(27)15-10-25-17(16(15)12(2)3)18(21-11-22-25)23-14-8-6-7-13(9-14)19(26)24-28-4/h6-12H,5H2,1-4H3,(H,24,26)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)				J Med Chem 48: 3991-4008 (2005) Article DOI: 10.1021/jm0501275 BindingDB Entry DOI: 10.7270/Q2KP81QN
					More data for this Ligand-Target Pair