BDBM50168509 CHEMBL188937::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-3-yl)-3,5-dimethoxy-4-methyl-benzamide

SMILES: COc1cc(cc(OC)c1C)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1

InChI Key: InChIKey=ASYWRGGARJFSPX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50168509 (CHEMBL188937 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1cc(cc(OC)c1C)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1 Show InChI InChI=1S/C23H28N2O5/c1-15-20(27-2)10-17(11-21(15)28-3)23(26)24-18-5-4-8-25(13-18)12-16-6-7-19-22(9-16)30-14-29-19/h6-7,9-11,18H,4-5,8,12-14H2,1-3H3,(H,24,26)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration required for binding affinity against mouse MCHr1 competing human neuronal IMR32 cells receptor in a radiometric binding ass...				Bioorg Med Chem Lett 15: 3412-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.023 BindingDB Entry DOI: 10.7270/Q26D5SHR
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50168509 (CHEMBL188937 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1cc(cc(OC)c1C)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1 Show InChI InChI=1S/C23H28N2O5/c1-15-20(27-2)10-17(11-21(15)28-3)23(26)24-18-5-4-8-25(13-18)12-16-6-7-19-22(9-16)30-14-29-19/h6-7,9-11,18H,4-5,8,12-14H2,1-3H3,(H,24,26)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration required for functional antagonism of MCH mediated Ca+2 release competing human IMR32 cells receptor in a FLIPRTM based assa...				Bioorg Med Chem Lett 15: 3412-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.023 BindingDB Entry DOI: 10.7270/Q26D5SHR
					More data for this Ligand-Target Pair