BDBM50168615 (S)-3-[(4'-Chloro-biphenyl-4-carbonyl)-methyl-amino]-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide::CHEMBL189043
SMILES: CN([C@@H]1CCN(C)C1)C(=O)N1CC[C@@H](C1)N(C)C(=O)c1ccc(cc1)-c1ccc(Cl)cc1
InChI Key: InChIKey=JKXQDEDKAMWMTC-PKTZIBPZSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50168615 ((S)-3-[(4'-Chloro-biphenyl-4-carbonyl)-methyl-amin...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description Binding affinity towards the human MCH-R1 receptor by displacing [125I]-Tyr13]-MCH radioligand in HEK293 cells, Data is average of 3 or more independ... | Bioorg Med Chem Lett 15: 3439-45 (2005) Article DOI: 10.1016/j.bmcl.2005.05.015 BindingDB Entry DOI: 10.7270/Q2T72H0F | |||||||||||
More data for this Ligand-Target Pair |