BDBM50168635 (S)-3-{[5-(4-Methoxy-2-methyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide::CHEMBL189756

SMILES: COc1ccc(-c2ccc(s2)C(=O)N(C)[C@H]2CCN(C2)C(=O)N(C)[C@@H]2CCN(C)C2)c(C)c1

InChI Key: InChIKey=IFEYOUAEYYSZDQ-MOPGFXCFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50168635 ((S)-3-{[5-(4-Methoxy-2-methyl-phenyl)-thiophene-2-...) Show SMILES COc1ccc(-c2ccc(s2)C(=O)N(C)[C@H]2CCN(C2)C(=O)N(C)[C@@H]2CCN(C)C2)c(C)c1 Show InChI InChI=1S/C25H34N4O3S/c1-17-14-20(32-5)6-7-21(17)22-8-9-23(33-22)24(30)27(3)19-11-13-29(16-19)25(31)28(4)18-10-12-26(2)15-18/h6-9,14,18-19H,10-13,15-16H2,1-5H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity towards the human MCH-R1 receptor by displacing [125I]-Tyr13]-MCH radioligand in HEK293 cells, Data is average of 3 or more independ...				Bioorg Med Chem Lett 15: 3439-45 (2005) Article DOI: 10.1016/j.bmcl.2005.05.015 BindingDB Entry DOI: 10.7270/Q2T72H0F
					More data for this Ligand-Target Pair