BDBM50168709 1-(3-Amino-3-thiophen-2-yl-propyl)-3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-[1,3,5]triazinane-2,4,6-trione::CHEMBL179023

SMILES: COc1cccc(c1)-n1c(=O)n(CCC(N)c2cccs2)c(=O)n(Cc2c(F)cccc2F)c1=O

InChI Key: InChIKey=PCPCJYQXCOEAMN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50168709 (1-(3-Amino-3-thiophen-2-yl-propyl)-3-(2,6-difluoro...) Show SMILES COc1cccc(c1)-n1c(=O)n(CCC(N)c2cccs2)c(=O)n(Cc2c(F)cccc2F)c1=O Show InChI InChI=1S/C24H22F2N4O4S/c1-34-16-6-2-5-15(13-16)30-23(32)28(11-10-20(27)21-9-4-12-35-21)22(31)29(24(30)33)14-17-18(25)7-3-8-19(17)26/h2-9,12-13,20H,10-11,14,27H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description In vitro ability to inhibit des-Gly[125I-Tyr, DLeu, NMeLeu,Pro-NEt]-GnRH radioligand binding to the cloned human GnRH receptor stably expressed in HE...				Bioorg Med Chem Lett 15: 3685-90 (2005) Article DOI: 10.1016/j.bmcl.2005.05.038 BindingDB Entry DOI: 10.7270/Q2DZ07TN
					More data for this Ligand-Target Pair