BDBM50168719 1-(3-Amino-2-phenyl-propyl)-3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-[1,3,5]triazinane-2,4,6-trione::CHEMBL177523

SMILES: COc1cccc(c1)-n1c(=O)n(CC(CN)c2ccccc2)c(=O)n(Cc2c(F)cccc2F)c1=O

InChI Key: InChIKey=GQKNFDQUITYUGA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50168719 (1-(3-Amino-2-phenyl-propyl)-3-(2,6-difluoro-benzyl...) Show SMILES COc1cccc(c1)-n1c(=O)n(CC(CN)c2ccccc2)c(=O)n(Cc2c(F)cccc2F)c1=O Show InChI InChI=1S/C26H24F2N4O4/c1-36-20-10-5-9-19(13-20)32-25(34)30(15-18(14-29)17-7-3-2-4-8-17)24(33)31(26(32)35)16-21-22(27)11-6-12-23(21)28/h2-13,18H,14-16,29H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description In vitro ability to inhibit des-Gly[125I-Tyr, DLeu, NMeLeu,Pro-NEt]-GnRH radioligand binding to the cloned human GnRH receptor stably expressed in HE...				Bioorg Med Chem Lett 15: 3685-90 (2005) Article DOI: 10.1016/j.bmcl.2005.05.038 BindingDB Entry DOI: 10.7270/Q2DZ07TN
					More data for this Ligand-Target Pair