BDBM50168798 1-(2-Biphenyl-4-yl-4-cyclopentylamino-butyl)-3-(3,5-dichloro-phenyl)-urea::CHEMBL179325

SMILES: Clc1cc(Cl)cc(NC(=O)NCC(CCNC2CCCC2)c2ccc(cc2)-c2ccccc2)c1

InChI Key: InChIKey=FALDQSPWCQAMAR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50168798 (1-(2-Biphenyl-4-yl-4-cyclopentylamino-butyl)-3-(3,...) Show SMILES Clc1cc(Cl)cc(NC(=O)NCC(CCNC2CCCC2)c2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H31Cl2N3O/c29-24-16-25(30)18-27(17-24)33-28(34)32-19-23(14-15-31-26-8-4-5-9-26)22-12-10-21(11-13-22)20-6-2-1-3-7-20/h1-3,6-7,10-13,16-18,23,26,31H,4-5,8-9,14-15,19H2,(H2,32,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Inhibitiory constant towards Human melanin-concentrating hormone receptor				Bioorg Med Chem Lett 15: 3691-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.039 BindingDB Entry DOI: 10.7270/Q2X066KC
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50168798 (1-(2-Biphenyl-4-yl-4-cyclopentylamino-butyl)-3-(3,...) Show SMILES Clc1cc(Cl)cc(NC(=O)NCC(CCNC2CCCC2)c2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H31Cl2N3O/c29-24-16-25(30)18-27(17-24)33-28(34)32-19-23(14-15-31-26-8-4-5-9-26)22-12-10-21(11-13-22)20-6-2-1-3-7-20/h1-3,6-7,10-13,16-18,23,26,31H,4-5,8-9,14-15,19H2,(H2,32,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126741
					More data for this Ligand-Target Pair