BDBM50168809 1-[2-(3'-Cyano-biphenyl-4-yl)-4-isopropylamino-butyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL368417

SMILES: CC(C)NCCC(CNC(=O)Nc1cc(Cl)cc(Cl)c1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=DNLHZFKGAAHGFI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50168809 (1-[2-(3'-Cyano-biphenyl-4-yl)-4-isopropylamino-but...) Show SMILES CC(C)NCCC(CNC(=O)Nc1cc(Cl)cc(Cl)c1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C27H28Cl2N4O/c1-18(2)31-11-10-23(17-32-27(34)33-26-14-24(28)13-25(29)15-26)21-8-6-20(7-9-21)22-5-3-4-19(12-22)16-30/h3-9,12-15,18,23,31H,10-11,17H2,1-2H3,(H2,32,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Inhibitiory constant towards Human melanin-concentrating hormone receptor				Bioorg Med Chem Lett 15: 3691-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.039 BindingDB Entry DOI: 10.7270/Q2X066KC
					More data for this Ligand-Target Pair