BDBM50168814 1-[2-(3'-Cyano-biphenyl-4-yl)-4-dimethylamino-butyl]-3-(4-fluoro-phenyl)-urea::CHEMBL175943

SMILES: CN(C)CCC(CNC(=O)Nc1ccc(F)cc1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=BMDHZRHPQPUCQS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50168814 (1-[2-(3'-Cyano-biphenyl-4-yl)-4-dimethylamino-buty...) Show SMILES CN(C)CCC(CNC(=O)Nc1ccc(F)cc1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C26H27FN4O/c1-31(2)15-14-23(18-29-26(32)30-25-12-10-24(27)11-13-25)21-8-6-20(7-9-21)22-5-3-4-19(16-22)17-28/h3-13,16,23H,14-15,18H2,1-2H3,(H2,29,30,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Inhibitiory constant towards Human melanin-concentrating hormone receptor				Bioorg Med Chem Lett 15: 3691-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.039 BindingDB Entry DOI: 10.7270/Q2X066KC
					More data for this Ligand-Target Pair