BDBM50168824 1-[2-(4'-Cyano-biphenyl-4-yl)-4-cyclopentylamino-butyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL177900

SMILES: Clc1cc(Cl)cc(NC(=O)NCC(CCNC2CCCC2)c2ccc(cc2)-c2ccc(cc2)C#N)c1

InChI Key: InChIKey=HFILRXVROWPKNX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50168824 (1-[2-(4'-Cyano-biphenyl-4-yl)-4-cyclopentylamino-b...) Show SMILES Clc1cc(Cl)cc(NC(=O)NCC(CCNC2CCCC2)c2ccc(cc2)-c2ccc(cc2)C#N)c1 Show InChI InChI=1S/C29H30Cl2N4O/c30-25-15-26(31)17-28(16-25)35-29(36)34-19-24(13-14-33-27-3-1-2-4-27)23-11-9-22(10-12-23)21-7-5-20(18-32)6-8-21/h5-12,15-17,24,27,33H,1-4,13-14,19H2,(H2,34,35,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Inhibitiory constant towards Human melanin-concentrating hormone receptor				Bioorg Med Chem Lett 15: 3691-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.039 BindingDB Entry DOI: 10.7270/Q2X066KC
					More data for this Ligand-Target Pair