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BDBM50168857 4-(1-Ethyl-4-phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamine::CHEMBL186343

SMILES: CCn1c(nc2c(nccc12)-c1ccccc1)-c1nonc1N

InChI Key: InChIKey=JYZSQHAEJSRWLL-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168857   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (human))
BDBM50168857
PNG
(4-(1-Ethyl-4-phenyl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Show SMILES CCn1c(nc2c(nccc12)-c1ccccc1)-c1nonc1N
Show InChI InChI=1S/C16H14N6O/c1-2-22-11-8-9-18-12(10-6-4-3-5-7-10)13(11)19-16(22)14-15(17)21-23-20-14/h3-9H,2H2,1H3,(H2,17,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 813n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration against MSK-1


Bioorg Med Chem Lett 15: 3407-11 (2005)

More data for this
Ligand-Target Pair