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BDBM50168858 (R,S)-4-(1-Piperidin-3-yl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamine::CHEMBL188806

SMILES: Nc1nonc1-c1nc2cnccc2n1C1CCCNC1

InChI Key: InChIKey=DBXWKNDVTAVTBK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168858   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168858
PNG
((R,S)-4-(1-Piperidin-3-yl-1H-imidazo[4,5-c]pyridin...)
Show SMILES Nc1nonc1-c1nc2cnccc2n1C1CCCNC1
Show InChI InChI=1S/C13H15N7O/c14-12-11(18-21-19-12)13-17-9-7-16-5-3-10(9)20(13)8-2-1-4-15-6-8/h3,5,7-8,15H,1-2,4,6H2,(H2,14,19)
PDB
MMDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration against MSK-1


Bioorg Med Chem Lett 15: 3407-11 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.020
More data for this
Ligand-Target Pair